TRANSFAC, TRRD and COMPEL: towards a federated database system on transcriptional regulation

E. Wingender , A. E. Kel1, O. V. Kel1 , H. Karas, T. Heinemeyer , P. Dietze , R. Knüppel , A. G. Romaschenko1, and N. A. Kolchanov1

Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-38124 Braunschweig, Germany and
1 Institute of Cytology and Genetics SB RAS, pr. Lavrentyeva-10, 630090 Novosibirsk , Russia

Nucleic Acids Research , 25(1):265-268 (Jan 1, 1997)

Abstract

Three databases that provide data on transcriptional regulation are described. TRANSFAC is a database on transcription factors and their DNA binding sites. TRRD (Transcription Regulatory Region Database) collects information about complete regulatory regions, their regulation properties and architecture. COMPEL comprises specific information on composite regulatory elements. Here, we describe the present status of these databases and the first steps towards their federation.