Rockefeller University
Weiss Building (Room 302)
1230 York Avenue, New York

ADVANCED GENE MAPPING COURSE
December 14-18, 2009

The course will be held every day from 9:00AM - 5:00PM in Room 302 of the Weiss Building on the Rockefeller University campus, located at 1230 York Avenue (entrance at 66th Street). On Wednesday evening, a special lecture will be given by Dr. Jurg Ott at 5:00 PM. On Monday evening a social gathering will be held at The Rockefeller University Faculty Club.

Each session will start with a theoretical introduction followed by practical exercises.  Instructors for the course are Goncalo Abecasis, Heather Cordell, Christoph Lange, Suzanne Leal and Shaun Purcell.

MONDAY - December 14

Instructor - Shaun Purcell
Whole Genome Association analysis - analysis of population based data qualitative traits

Exercises: PLINK

Evening Program

5:30PM Get-together for course participants and instructors at The Rockefeller Faculty Club.

TUESDAY - December 15

Instructor - Heather Cordell

Whole genome association studies of quantitative traits population and family based data, Controlling for population admixture/substructure

Exercises: GenABEL, QTDT

WEDNESDAY - December 16

Instructor - Goncalo Abecasis
Imputation of genotype data for pedigrees and case-control data; Meta Analysis of association data; Association analysis of population and family based data

Exercises: MACH, METAL, LAMP

Evening Program

5:00PM Special Lecture - Jurg Ott
Multi-locus Association Mapping Methods

THURSDAY - December 17

Instructor - Suzanne Leal

Data quality control; Gene x gene interaction (linear and logistic regression, MDR, CART); Sample size and Power estimation (main effects & gene x gene and gene x environmental interaction); Permutation; False discovery rate; Analysis of rare variants

Exercises: R, MDR, Quanto

FRIDAY - December 18

Instructor – Christoph Lange
Family based association analysis of quantitative and qualitative traits

Exercises: P2BAT