Rockefeller University
ADVANCED GENE MAPPING COURSE
December 10-14, 2007
The course will be held every day from 9:00AM - 5:00PM in Room 302 of the Weiss Building on the Rockefeller University campus, located at 1230 York Avenue (entrance at 66th Street). On Wednesday, a special lecture will be given by Dr. Jurg Ott at 5:00 PM. On Monday evening a social gathering will be held at The Rockefeller University Faculty Club.
Each session will start with a theoretical introduction followed by practical exercises. Instructors for the course are Goncalo Abecasis, Laura Almasy, David Clayton, Heather Cordell and Suzanne Leal.
MONDAY - December 10
Instructor - Heather Cordell
Non-parametric linkage analysis of pedigree data and sib-pair data for qualitative and quantitative traits.
Exercises: GENEHUNTER, ALLEGRO
Evening Program
5:30PM Get-together for course participants and instructors at The Rockefeller Faculty Club.
TUESDAY - December 11
Instructor - Laura Almasy
Variance Component Analysis
Exercises: SOLAR
WEDNESDAY - December 12
Instructor - Suzanne Leal
Sample size estimation and power Analysis (pedigree, sib-pair and case control data);
Estimation of empirical p-values; controling for multiple testing; False Discovery Rate.
Exercises: COCAPHASE, PAWE, Genetic Power Calculator, SIMPED, DESPAIR, PS
Evening Program
5:00PM Special Lecture - Jurg Ott
Genetic and non-genetic risk factors in case-control association studies.
THURSDAY - December 13
Instructor - Goncalo Abecasis
Family based association analysis; Population based association analysis
Exercises: MERLIN, GWava (Genome Wide Association Visual Analysis)
FRIDAY - December 14
Instructor - David Clayton
Test of association for quantitative and qualitative traits for
samples of unrelated and related individuals;
Controlling for population admixture/substructure;
and tagSNP selection.
Exercises with R