mdc_bioinf.png    Max Delbrück Center for Molecular Medicine

                       -Department of Bioinformatics -


Basic Gene Mapping Course

November 9-13, 2009
Max Delbrück Center (MDC) for Molecular Medicine
Berlin, Germany


A basic gene mapping\linkage course will be held at the MDC in Berlin from November, 9-13, 2009. The course will be held on the fourth floor in the Dendrit II+III rooms of the communications center (conference center) at the MDC.  This course was previously called the basic linkage course, the name has been changed to reflect the expanded scope of the course in the past few years. The goal of the course is to teach the course participants both theory and application of methods for linkage analysis (parametric and nonparametric) and association studies.

The cost of the 5 day course is 875 EUR for researchers from an academic institution, and 1,675 EUR for individuals from private (for profit) companies. This fee covers tuition, wine and cheese party and course related expenses (handouts, etc.) but not room, board or meals. Inexpensive housing is available for course participants at the MDC.

The maximum number of participants is 30. Emphasis in this course is on strategies for genetic mapping of human Mendelian and complex traits. It will include theory as well as practical exercises. The exercises will be carried out using a variety of computer programs (LINKAGE, GENEHUNTER, MERLIN, ALLEGRO, SIMWALK2, SLINK, PLINK, TAGGER, etc.) and with pencil and paper. TOPICS include: parametric methods (two-point and multipoint analysis); allele sharing (nonparametric) methods for sib-pairs and extended families (two-point and multipoint analysis);  linkage admixture (heterogeneity); tagSNP selection, haplotype reconstruction, association studies (trios and case-control); data quality control; controlling for population admixture/substructure; sample size estimation and power estimation (extended families [simulation studies], sib-pairs and case-control data), controlling the family wise error rate (FWER) and estimating empirical p-values. The organizers and instructors for the course are Suzanne Leal (Baylor College of Medicine) and Michael Nothnagel (Kiel University & Max Delbrück Center).

For additional information please contact Suzanne Leal:

Click here for the application form

Click here for the course schedule

Click here for course flyer (Please post and distribute)

Click here for directions to the MDC

Click here for map showing directions to the MDC

Click here for Google maps directions and map to get to the MDC

Click here for the information on MDC Housing

Click here for information on the MDC communication center (conference center)

Click here for useful links (Hotels, Berlin tourist information, etc.)

Click here for photos from the Basic Gene Mapping Course, Berlin, July 2008

Click here for photos from the Basic Gene Mapping Course, Berlin, July 2007

Click here for photos from the Basic Gene Mapping Course, Berlin, July 2006

Click here for photos from the Basic Gene Mapping Course, Berlin, July 2005

Click here for photos from the Basic Gene Mapping Course, Berlin, July 2004

Click here for photos from the Basic Gene Mapping Course, Berlin, July 2003