the first few columns are identical to the pre-MAKEPED file col 1: pedigree ID col 2: person ID col 3: father ID col 4: mother ID three extra columns generated by MAKEPED col 5: first offspring ID col 6: next parental sibling ID col 7: next maternal sibling ID back to pre-MAKEPED file: col 8: gender (1 for male, 2 for female) one more extra column generated by MAKEPED (total 4 extra columns) col 9: proband status (related to the "leading person" and "loop breaking" persons in the pedigree. otherwise 0) back to pre-MAKEPED file: col 10: affection status the next column is optional (be careful! since you don't know whether you have this column or not until you check the LINKAGE parameter file): the liability class this person belongs to. the rest are the marker information. note that one marker contributes two columns, for both parents, although it is not clear which one is from father and which is from mother. the coding of the marker allele values is arbitrary as long as it is consistent.