Presymptomatic Exclusion of Myotonic Dystrophy in a One-Generation
Pedigree of Half-Siblings
J. Ott, J. Caesar, M. Machler, A. Schinzel, W. Schmid
Human Heredity , 40(5), 305--307 (1990)
Abstract
An unusual one-generation family with myotonic dystrophy is
presented, in which genetic counseling was successfully carried out.
The probability of an informative result, before marker typing, is
analytically derived and amounts to at least 40%.
