Jurg Ott
Institute of Psychology, CAS, Beijing
Rockefeller University, New York

9 Jan 2012

Instructions for the use of the FP test

The theory of this association test may be found in the manuscript listed below (Zhang et al 2008). Download the program package (FPtest.zip) and move its contents into a folder. Preferably, run the FPtest program in a Windows command window (CMD), or double-click on FPtest (FPtest.exe).

The program will compute p-values via permutation samples, with the observed data being counted as a null dataset. Thus, the smallest p-value that can be obtained is 1/n, where n is the number of permutations performed. Choose a suitably large number of permutation samples such as 20,000 or more. The program will write output to a file called FPtestout.txt.

Reference for sample data

Zhang Q, Wang S, Ott J. Combining identity by descent and and association in genetic case-control studies. BMC Genetics 2008, 9:42