The investigation of linkage between a quantitative trait and a marker locus

J.K. Haseman, R.C. Elston

Behavior Genetics , 2(1), 3-19 (1972)


Abstract

Procedures are given, using sib pairs, for estimating linkage between a known m-allele locus and a hypothesized two-allele locus that governs a quantitative trait. Random mating and linkage equilibrium are assumed. Also, given are parametric and nonparametric methods for detecting linkage when the trait in question is governed by several two-allele loci, provided there is no epistasis.

Allele-sharing linkage analysis